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Last update : april 17, 2004

Nitrofurantoin****

Patterns : I (a) : Acute cellular interstitial lung disease/pneumonia
I (b) : Subacute interstitial pneumonia. Similar to but less severe than 1a
I (c) : Pulmonary infiltrates and eosinophilia. Eosinophilic pneumonia (also see 10a)
I (d) : Organising pneumonia ( BOOP - AFOP)
I (e) : Desquamative interstitial pneumonia (DIP pattern)
I (g) : Pulmonary fibrosis
I (l)* : Diffuse alveolar damage (DAD)
II (b) : Acute severe pulmonary oedema / ARDS
III (a) : Diffuse alveolar hemorrhage w/wo ANCA
IV (a) : Acute bronchospasm
IV (b) : Bronchospasm and angioedema w/wo anaphylaxis
V (a) : Pleural effusion (also see 5b, 5d)
V (d) : Pleural effusion in drug-induced lupus syndrome
VI (d) : Pulmonary vasculitis
VIII (b) : Peritracheal/mediastinal hemorrhage and upper airway obstruction
X (a) : Skin rash, eosinophilia, and internal organs involvement including pneumonia (DRESS)
XI (b) : Isoleted acute chest pain
XI (c) : Acute chest pain and interstitial lung disease

1. Velema MS, Voerman HJ. DRESS syndrome caused by nitrofurantoin. Neth J Med. 2009 Apr;67(4):147-9.

2. Fawcett I W, Ibrahim N B N. BOOP associated with nitrofurantoin. Thorax 2001; 56: 161

3. Cameron R J, Kolbe J, Wilsher M L, Lambie N. Bronchiolitis obliterans organising pneumonia associated with the use of nitrofurantoin. Thorax 2000; 55: 249-351

4. Sheehan R E, Wells A U, Milne D G, Hansell D M. Nitrofurantoin-induced lung disease: Two cases demonstrating resolution of apparently irreversible CT abnormalities. Journal of Computer Assisted Tomography 2000; 24: 259-261

5. Cameron C, Bayliff C D, Patterson N A M. Nitrofurantoin-associated acute pulmonary toxicity. Canadian Journal of Hospital Pharmacy 1999; 52: 83-6

6. Basoglu T, Erkan L, Canbaz F, Bernay I, Onen T, Sahin M, Furtun F, Yalin T. Transient reverse ventilation-perfusion mismatch in acute pulmonary nitrofurantoin reaction. Ann Nucl Med 1997; 11: 271-274

7. Bayliff C D, Sobiera C J, Paterson N A M. Nitrofurantoin induced acute pneumonitis. A review of three cases. Can J Hosp Pharm 1997; 50: 247

8. Zielonka T M, Demkow U, Kus J. Pulmonary reaction after furazidin (Furagin). Case report. Pol Arch Med Wewn 1997; 97: 465-472

9. Boggess K A, Benedetti T J, Raghu G. Nitrofurantoin-induced pulmonary toxicity during pregnancy: a report of a case and review of the literature. Obstet Gynecol Surv 1996; 51: 367-370

10. Pfitzenmeyer P, Lacroix D, Piard F, Foucher P, Camus P. Pneumopathie interstitielle desquamative et nitrofurantoïne. In: Brambilla C, Brambilla, E., ed. Confrontations radio-anatomo-cliniques. Paris: Cassenne; 1996: 70

11. Ficheroulle X, Macquet M, Rogeaux Y, Macquet Y. Pneumopathie interstitielle fibrosante mortelle de cause inhabituelle. Rev Mal Respir 1995; 12: 175-176

12. Vincent F, Bensoussan T A. Nitrofurantoin-induced pulmonary hemorrhage in a renal transplant recipient receiving immunosuppressive therapy. J Urol 1995; 154: 214

13. Cohen A J, King T E, Jr, Downey G P. Rapidly progressive bronchiolitis obliterans with organizing pneumonia. Am J Respir Crit Care Med 1994; 149: 1670-1675

14. Meyer M M, Meyer R J. Nitrofurantoin-induced pulmonary hemorrhage in a renal transplant recipient receiving immunosuppressive therapy: case report and review of the litterature. J Urol 1994; 152: 938-940

15. Lenci G, Müller-Quernheim J, Lorenz J, Ferlinz R. Pulmonale Toxizität durch Nitrofurantoin. Pneumologie 1993; 47: 518-523

16. Lee N K K, Slavin J D, Jr, Spencer R P. Ventilation-perfusion lung imaging in nitrofurantoin-related pulmonary reaction. Clin Nucl Med 1992; 17: 94-96

17. Padley S P G, Adler B, Hansell D M, Müller N L. High-resolution computed tomography of drug-induced lung disease. Clin Radiol 1992; 46: 232-236

18. Perez-Herms S, Castellanos Acosta R, Guzman Fernandez A, Cortadellas Angel R, Ballesteros Sampol J J. Fibrosis pulmonar secundaria a nitrofurantoina. Arch Esp Urol 1992; 45: 577-578

19. Reinhart H H, Reinhart E, Korlipara P, Peleman R. Combined nitrofurantoin toxicity to liver and lung. Gastroenterology 1992; 102: 1396-1399

20. Russi E. Toxic and drug-induced lesions of the pulmonary parenchyma. Schweiz Rundsch Med Prax 1992; 81: 618-621

21. Yamakado S, Yoshida Y, Yamada T, Kishida T, Kobayashi M, Nomura T. Pulmonary infiltration and eosinophilia associated with sulfasalazine therapy for ulcerative colitis: a case report and review of the literature. Intern Med 1992; 31: 108-113

22. Akoun G M, Cadranel J L, Milleron B J, Flammang D'Ortho M P, Mayaud C M. Bronchoalveolar lavage cell data in 19 patients with drug-associated pneumonitis (except amiodarone). Chest 1991; 99: 98-104

23. Lingenfelser T, Pfohl M, Grauer W, Becker W, Wakat P, Jakober B, Dölle W. Nitrofurantoin-induzierte Hepatitis und Pneumonitis. Münch Med Wschr 1991; 133: 495-498

24. Moinuddin M. Radionuclide scanning in the detection of drug-induced lung disorders. J Thorac Imaging 1991; 6: 62-67

25. Pietra G G. Pathologic mechanisms of drug-induced lung disorders. J Thorac Imaging 1991; 6: 1-7

26. Frolich J C. Unwanted effects of therapeutic drugs on the structure and function of the lung from a clinico-pharmacologic viewpoint. Pneumologie 1990; 44 Suppl 1: 167-172

27. Martin W J. Pulmonary toxicity induced by chemical agents. Eur Respir J 1990; 3: 375-376

28. Mihaltan F. Toxic pulmonary and neuronal reactions to nitrofurantoin. Rev Ig Med Muncii Med Soc Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol 1990; 39: 51-58

29. Winterbauer R H, Hammar S P, Hallman K O, al. e. Diffuse interstitial pneumonitis: clinicopathologic correlations in 20 patients treated with prednisone/azathioprine. Am J Med 1990; 65: 661-662

30. Chudnovsky C R, Otten E J. Acute pulmonary toxicity to nitrofurantion. J Emerg Med 1989; 7: 15-19

31. Jick S S, Jick H, Walker A M, Hunter J R. Hospitalizations for pulmonary reactions following nitrofurantoin use. Chest 1989; 96: 512-515

32. Witten C M. Pulmonary toxicity of nitrofurantoin. Arch Phys Med Rehabil 1989; 70: 55-57

33. Hakala M. Poor prognosis in patients with rheumatoid arthritis hospitalized for interstitial lung fibrosis. Chest 1988; 93: 114-118

34. Bucknall C E, Adamson M R, Banham S W. Non fatal pulmonary haemorrhage associated with nitrofurantoin. Thorax 1987; 42: 475-476

35. Colquhoun J P. Beware the yellow pearl! Aust Fam Physician 1987; 16: 1505

36. Nyvad O, Jensen P H. Nitrofurantoin-induced lung edema. Ugeskr Laeger 1987; 149: 851-852

37. Chapman J A. An unusual nitrofurantoin-induced drug reaction. Ann Allergy 1986; 56: 16-18

38. Akoun G M, Milleron B, El Gharbi N, Malka M. Le lavage bronchoalvéolaire dans la pneumopathie de la nitrofurantoïne. Sem Hop Paris 1985; 61: 2443-2446

39. Akoun G M, Mayaud C M, Milleron B J, Perrot J Y. Drug-related pneumonitis and drug-induced hypersensitivity pneumonitis. Lancet 1984; i: 1362

40. Bargon G. Drug-induced changes in the lungs. Röntgenblatter 1984; 37: 261-265

41. Clark B G, Vestal R E. Adverse drug reactions in the elderly: case studies. Geriatrics 1984; 39: 53-4, 60-3, 66

42. Heymans G, Soupart A. Drug-induced pneumopathies (excluding anticancer drugs). Rev Med Brux 1984; 5: 279-283

43. Qureshi M M. Interstitial lung disease caused by chronic nitrofurantoin reaction; case report. Wis Med J 1984; 83: 20-22

44. Cannon G W, Ward J R, Clegg D O, Samuelson C O, Jr, Abbott T M. Acute lung disease associated with low-dose pulse methotrexate therapy in patients with rheumatoid arthritis. Arthr Rheum 1983; 26: 1269-1274

45. Hurtado J, Diaz Curiel M, Fernandez Guerrero M L, Garcia Delgado R, Lahoz Navarro C, Corella I, Marin Hernandez G. Neumonitis por nitrofurantoina. Bol Fund Jimenez Diaz 1983; 10: 315-?

46. Lebecque F, Mairesse M. Pneumopathie à la nitrofurantoïne. Poumon Coeur 1983; 39: 101-108

47. Robinson B W S. Nitrofurantoin-induced interstitial pulmonary fibrosis. Med J Aust 1983; 1: 72-76

48. Andersson K E, Bucht H, Fjellstrom K E, Hovelius B, Bengtsson U, Erlandsson P, Fritz H, Lingqvist B, Orsten P A. Fatal cases after treatment with sulfonamide and nitrofurantoin. Lakartidningen 1982; 79: 402-406

49. Crook M J, Kaplan P D, Adatepe M H. Gallium-67 scanning in nitrofurantoin-induced pulmonary reaction. J Nucl Med 1982; 23: 690-692

50. Penn R G, Griffin J P. Adverse reactions to nitrofurantoin in the United Kingdom, Sweden and Holland. Br Med J 1982; 284: 1440-1442

51. van Rensburg W. Pulmonary fibrosis following long-term nitrofurantoin therapy. S Afr Med J 1982; 62: 716-717

52. Willcox P A, Maze S S, Sandler M, Benatar S R. Pulmonary fibrosis following long-term nitrofurantoin therapy. S Afr Med J 1982; 61: 714-717

53. Hainer B L, White A A. Nitrofurantoin pulmonary toxicity. J Fam Pract 1981; 13: 817-823

54. Holmberg L, Boman G. Pulmonary reactions to nitrofurantoin. 447 cases reported to the Swedish Adverse Drug Reaction Committee 1966-1976. Eur J Respir Dis 1981; 62: 180-189

55. Averbuch S D, Yungbluth P. Fatal pulmonary hemorrhage due to nitrofurantoin. Arch Intern Med 1980; 140: 271-273

56. Faling L J, Petusevsky M L, Snider G L. Nitrofurantoin and dantrolene; liver and lung. Ann Intern Med 1980; 93: 151

57. Formgren H, Lindgren S, Ahlstedt S, Zettergren L, Hanson L A. Histopathological findings and immune response against nitrofurantoin in drug intolerance pneumonitis. Vol. 2 Basel: Karger; 1980. (Dukor P, Kallos P, Schlumberger H D, West G B, eds. Pseudo-allergic reactions. Involvement of drugs and chemicals)

58. Israel R H, Gross R A, Bomba P A. Adult respiratory distress syndrome associated with acute nitrofurantoin toxicity. Respiration 1980; 39: 318-322

59. Jayasundera N S, Johnson R D, Nicholson D P. Chronic pulmonary reaction to nitrofurantoin. JAMA 1980; 243: 769

60. Prakash U B S. Pulmonary reaction to nitrofurantoin. Semin Respir Med 1980; 2: 70-75

61. Robinson G M, Bai T R, Steele R H. Nitrofurantoin induced chronic pulmonary reaction: case report. NZ Med J 1980; 91: 50-52

62. Ancic P, Ferretti R. Chronic pulmonary reaction after nitrofurantoin. Rev Med Chil 1979; 107: 319-323

63. Filipek W J. Drug-induced pulmonary disease. Postgrad Med 1979; 65: 131-6, 139-40

64. Formgren H, Lindgren S, Ahlstedt S, Zettergren L, Hanson L A. Histopathological findings and immune response to nitrofurantoin in drug intolerance pneumonitis. Br J Dis Chest 1979; 73: 420

65. Gleckman R, Alvarez S, Joubert D W. Drug therapy reviews: nitrofurantoin. Am J Hosp Pharm 1979; 36: 342-351

66. Rantala H, Kirvelä O, Anttolainen I. Nitrofurantoin lung in a child. Lancet 1979; ii: 799-800

67. Stableforth D E. Chronic lung disease. Pulmonary fibrosis. Br J Hosp Med 1979; 22: 128, 132-5

68. Vilaseca Momplet J, Ballester Rodes M. Reacciones pulmonares por nitrofurantoina. Rev Clin Esp 1979; 152: 177-181

69. Fritzler M J, Tam E M. Antibodies to histones in drug-induced and idiopathic lupus erythematosus. J Clin Invest 1978; 62: 560-567

70. Mairesse M, Ledent C. Pneumopathie sur nitrofurantoine. Lille Med 1978; 23: 331-335

71. Böttiger L E, Westerholm B. Adverse drug reactions during treatment of urinary tract infections. Eur J Clin Pharmacol 1977; 11: 439-442

72. Medici T C, Fontana A. Medikamentöse Lungenerkrankungen. Schweiz Med Wochenschr 1977; 107: 162-171

73. Simonian S J, Kroeker E J, Boyd D P. Chronic interstitial pneumonitis with fibrosis after long-term therapy with nitrofurantoin. Ann Thorac Surg 1977; 24: 284-288

74. Sovijärvi A R A, Lemola M, Stenius B, Idänpaan-Heikkilä J. Nitrofurantoin-induced acute, subacute and chronic pulmonary reactions. A report of 66 cases. Scand J Respir Dis 1977; 58: 41-50

75. Taskinen E, Tukainen P, Sovijärvi A R A. Nitrofurantoin-induced alterations in pulmonary tissue. Acta Pathol Microbiol Scand 1977; Sect A, 85: 713-720

76. Bone R C, Wolfe J, Sobonya R E, Kerby G R, Stechschulte D, Ruth W E, Welch M. Desquamative interstitial pneumonia following chronic nitrofurantoin therapy. Chest 1976; 69: 296-297

77. Bone R C, Wolfe J, Sobonya R E, Kerby G R, Stechschulte D, Ruth W E, Welch M. Desquamative interstitial pneumonia following long-term nitrofurantoin therapy. Am J Med 1976; 60: 697-701

78. Furhoff A K. Pulmonary reactions after treatment with nitrofurantoin. Lakartidningen 1976; 73: 3910

79. Geller M, Dickie H A, Kass D A, Hafez G R, Gillepsie J J. The histopathology of acute nitrofurantoin-associated pneumonitis. Ann Allergy 1976; 37: 275-279

80. Swierenga J. Lung disorders caused by drugs. Ned Tijdschr Geneeskd 1976; 120: 685-688

81. Kursch E D, Mostyn E M, Persky L, al e. Nitrofurantoin pulmonary complications. J Urol 1975; 113: 392-395

82. Lundgren R, Bäck O, Wiman L G. Pulmonary lesions and auto-immune reactions after long-term nitrofurantoin treatment. Scand J Respir Dis 1975; 56: 208-216

83. Melillo G, d'Amato G, Cocco G. Un cas de fibrose pulmonaire iatrogène par nitrofurantoine. Rev Fr Mal Respir 1975; 3: 667-671

84. Pauwels R, Dierickx S, Verstraeten P, van der Straeten M. Pulmonary disorders after intake of nitrofurantoin. About two cases. Acta Tuberc Pneumol Belg 1975; 66: 414-420

85. Ross D, Drevets C. Nitrofurantoin pulmonary reaction. J Kan Med Soc 1975; 76: 163-165

86. Selroos O, Edgren J. Lupus-like syndrome associated with pulmonary reaction to nitrofurantoin. Acta Med Scand 1975; 197: 125-129

87. Tukiainen. Needle biopsy in diffuse lung manifestations. An analysis of 145 consecutive cases. Scand J Respir Dis 1975; 94 Suppl: 1-110

88. Anonymous. Case Records of the Massachusetts General Hospital - Case 22-1974. N Engl J Med 1974; 290: 1309-1314

89. Bäck O, Lundgren R, Wiman L-G. Nitrofurantoin-induced pulmonary fibrosis and lupus syndrome. Lancet 1974; i: 930

90. Gieger E L, Jr. Radiologic seminar CXXXXV: nitrofurantoin lung disease. J Miss State Med Assoc 1974; 15: 482-483

91. Goldstein R A, Janicki B W. Immunologic studies in nitrofurantoin induced pulmonary disease. Med Ann Dist Columbia 1974; 43: 115-119

92. Guardia J, Pilar Tornos M, Villalonga C, Martinez-Vazquez J M. Reaccion pulmonar por furantooina. Rev Clin Esp 1974; 135: 285-287

93. Krauss J. Chronic nitrofurantoin-induced pulmonary syndrome. Z Allgemeinmed 1974; 50: 1293-1297

94. Müller W F H. Pulmonary reactions to furantoin. Radiol Clin Biol 1974; 43: 540-548

95. Pearsall H R, Ewalt J, Tsoi M S, Backus S D, Winterbauer R H, Webb D R, Jones H. Nitrofurantoin lung sensitivity: report of a case with prolonged nitrofurantoin lymphocyte sensitivity and interaction of nitrofurantoin-stimulated lymphocytes with alveolar cells. J Lab Clin Med 1974; 83: 728-737

96. Pinerua R F, Hartnett B J S. Acute pulmonary reaction to nitrofurantoin. Thorax 1974; 29: 599-602

97. Selroos O, Edgren J. Pulmonary reactions to nitrofurantoin. Scand J Respir Dis 1974; Suppl 88: 40

98. Strandberg I, Wengle B, Fagrell B. Chronic interstitial pneumonitis with fibrosis during long-term treatment with nitrofurantoin. Acta Med Scand 1974; 196: 483-487

99. Haas W, Münzenmaier R, Loewe K R. Beitrag zur Frage des Nitrofurantoin-induzierte chonische Lungenfibrose. Dtsch Med Wochenschr 1973; 98: 1867-1871

100. Heap T R, Rebuck A S. Pulmonary fibrosis and nitrofurantoin. Australas Radiol 1973; 108: 353-356

101. Israel K S, Brashear R E, Sharma H M, Yum M N, Glover J L. Pulmonary fibrosis and nitrofurantoin. Am Rev Respir Dis 1973; 108: 353-356

102. Larsson S, Cronberg S, Denneberg T, Ohlsson N M. Pulmonary reaction to nitrofurantoin. Scand J Respir Dis 1973; 54: 103-110

103. Stein J J, Martin D C. Nitrofurantoin pulmonary hypersensitivity reaction. J Urol 1973; 110: 577-578

104. Uthgenannt H, Lübbers P, Gappmayer K. Allergische Reaktionen der Lunge durch Arzneimittel. Fortschr Roentgenstr 1973; 118: 125-136

105. Barthel E. Nitrofurantoin und Lungenfibrose. Dtsch Gesundh Wes 1972; 27: 977

106. Bouhuys A, Rose M C, Cosentino A M, McCombs R P. Pulmonary reactions to nitrofurantoin and in byssinosis. N Engl J Med 1972; 287: 308-309

107. Cortez L M, Pankey G A. Acute pulmonary hypersensitivity to furazolidone. Am Rev Respir Dis 1972; 105: 823-826

108. Heap T R, Rebuck A S. Chronic nitrofurantoin (Furadantin) pulmonary reaction. Aust Radiol 1972; 16: 236-237

109. Plavnic L, Kanter Y, Barzilai D. Progressive dyspnea and pulmonary infiltration due to nitrofurantoin. Harefuah 1972; 83: 375-377

110. Szentklaray J. Allergic reaction of the lung during nitrofurantoin therapy. Orv Hetil 1972; 113: 325-326

111. Teigelkotter P. Chronic lung changes following nitrofurantoin medication. Fortschr Geb Rontgenstr Nuklearmed 1972; 117: 526-529

112. Teigelkötter P. Chronische Lungenveränderungen nach Nitrofurantoin-Medikation. Fortschr Röntgenstr 1972; 117: 526-?

113. Bachman A. Lunge und Nitrofurantoin. Dtsch Med Wochenschr 1971; 96: 1731

114. Bapna B C, Iyer N A, Rao D V. Unusual pulmonary complication of nitrofurantoin therapy. J Indian Med Assoc 1971; 57: 292-293

115. Koch-Weser J, Sidel V W, Dexter M, Parish C, Finer D C, Kanarek P. Adverse reactions to sulfisoxazole, sulfamethoxazole, and nitrofurantoin. Manifestations and specific reaction rates during 2,118 courses of therapy. Arch Intern Med 1971; 128: 399-404

116. Müller U K, Hoigné R. Lunge und Nitrofurantoin. Dtsch Med Wochenschr 1971; 96: 955-956

117. Ngan H, Millard R J, Lant A F, Trapnell D H. Nitrofurantoin lung. Br J Radiol 1971; 44: 21-23

118. Roosenburg J G. Chronische longreaktie na gebruik van nitrofurantoine. Ned T Geneesk 1971; 115: 370

119. Ruikka I, Vaissalo T, Saarimaa H. Progressive pulmonary fibrosis during nitrofurantoin therapy. A case history with autopsy report. Scand J Respir Dis 1971; 52: 162-166

120. Smith H T, Berkseth R. Pulmonary reaction to nitrofurantoin. Minn Med 1971; 54: 989-990

121. Tangen T L. Lung complications following use of Furadantin. Tidsskr Nor Laegeforen 1971; 91: 2406-2407

122. Wagner A. Chronische interstitielle Pneumonie mit Lungenfibrose durch Nitrofurantoin-Langzeittherapie. Med Klin 1971; 66: 1808-1811

123. Altschuler G. Nitrofurantoin lung disease. Ariz Med 1970; 27: 101-103

124. Anonymous. Lung diseases caused by nitrofurantoin. Tidsskr Nor Laegeforen 1970; 90: 113

125. Evans S. Pulmonary sensitivity to nitrofurantoin. Br Med J 1970; i: 235

126. Hart J. Pulmonary sensitivity to nitrofurantoin. Br Med J 1970; i: 51-52

127. Heijer A. Pleuro-pulmonary allergic reaction to nitrofurantoin. Acta Allergol 1970; 25: 63-69

128. Juby B A. Pulmonary sensitivity to nitrofurantoin. Br Med J 1970; i: 236

129. Morgan L K, Bendigo V. Nitrofurantoin pulmonary hypersensitivity. Med J Aust 1970; 2: 136-139

130. Müller U, Abbuhl K, Bisig J, Baumgartner H, Muhlberger F, Scherrer M, Hoigne R. Hypersensitivity of lungs against nitrofurantoin. Helv Med Acta Suppl 1970;: Suppl 50:131

131. Müller U, Abbühl K, Bissig J, Baumgartner H, Mühlberger F, Scherrer M, Hoigné R. Überempfindlichkeitsreaktionen der Lunge auf Nitrofurantoin. Schweiz Med Wschr 1970; 100: 2206-2212

132. Wiontzek H. Pulmonale Erscheinungen als Ausdruck einer Nitrofurantoin-Allergie. Prax Pneumol 1970; 24: 20-23

133. Anonymous. Lung disease caused by drugs. Br Med J 1969; 3: 729-730

134. Anonymous. Pulmonary sensitivity to nitrofurantoin. Br Med J 1969; ii: 704

135. Brander L, Selroos O. Pulmonary reaction to nitrofurantoin. Acta Med Scand 1969; 185: 215-220

136. Carrington C B, Addignton W W, Golf A, Madoff I M, Marks A, Schwaber J R, Gaensler E A. Chronic eosinophilic pneumonia. N Engl J Med 1969; 280: 787-798

137. Glueck M A, Janower M L. Nitrofurantoin lung disease. Clues to pathogenesis. Am J Roentgenol 1969; 107: 818-822

138. Hailey F J, Glascock H W J, Hewitt W F. Pleuropneumonic reactions to nitrofurantoin. N Engl J Med 1969; 281: 1087-1090

139. Harrow B R. Pulmonary reaction to nitrofurantoin. N Engl J Med 1969; 280: 389

140. Howard E J. Pulmonary reaction to nitrofurantoin. N Engl J Med 1969; 266: 1024-1026

141. Jameson S. Allergic pulmonary complications during treatment with nitrofurantoin. Scand J Urol Nephrol 1969; 3: 50-52

142. Lübbers P. Nitrofurantoin-Fieber. Dtsch Med Wochenschr 1969; 94: 1922-1927

143. Ochsner S F, Hatch H B, Leonard G L. Hypersensitivity and the lung. Am J Roentgenol 1969; 107: 290-299

144. Radecka-Skoglundh I. Pleuropulmonell allergisk reaktion mot nitrofurantoin. Läkartidningen 1969; 66: 854-856

145. Allen R W, Holt A H, Brown M G. Acute pulmonary sensitivity to nitrofurantoin. Am J Roentgenol 1968; 104: 784-786

146. Anonyme. Syndrome pulmonaire aigu de la nitrofurantoïne. Med Hyg 1968; 26: 896

147. Anonymous. Chronic reactions to drugs ? JAMA 1968; 206: 2842

148. Chow W S W, Mc Intyre W B. Pulmonary reaction of nitrofurantoin. A case report. Grace Hosp Bull 1968; 46: 51-56

149. David R B, Andersen H A, Stickler G B. Nitrofurantoin sensitivity: report of a child with chronic inflammatory lung disease. Am J Dis Child 1968; 116: 418-421

150. Nicklaus T M, Snyder A B. Nitrofurantoin pulmonary reaction: unique syndrome. Arch Intern Med 1968; 121: 151-155

151. Rosenow E C I, DeRemee R A, Dines D E. Chronic nitrofurantoin pulmonary reaction: report of five cases. N Engl J Med 1968; 279: 1258-1262

152. van de Kroon A A. Lung disorders in treatment with nitrofurantoin. Ned Tijdschr Geneeskd 1968; 112: 1349

153. Vaughan Jones R, Goldman L. Persistent eosinophilia after nitrofurantoin. Lancet 1968; i: 306

154. Wilson E S, Jr, McCarty R J. Nitrofurantoin pneumonia. Am J Roentgenol 1968; 103: 540-542

155. DeMasi C J. Allergic pulmonary infiltrates probably due to nitrofurantoin. Arch Intern Med 1967; 120: 631-634

156. Deodhar S D, Bhagwat A G. Desquamative interstitial pneumonia-like syndrome in rabbits. Produced experimentally by Freund's adjuvant. Arch Pathol 1967; 84: 54-58

157. Frankenfeld R H. Pulmonary edema caused by nitrofurantoin. Ann Intern Med 1967; 66: 1055

158. Morris A J. Pulmonary and eosinophilic reaction to nitrofurantoin. Del Med J 1967; 39: 299-301

159. Strauss W G, Griffin L M. Nitrofurantoin pneumonia. JAMA 1967; 199: 175-176

160. Tiszai A S, Tiszai G. Nitrofurantoinpneumonia. Orv Hetil 1967; 108:

161. Dawson R B, Jr. Pulmonary reactions to nitrofurantoin. N Engl J Med 1966; 274: 522

162. Murphy K J. Pulmonary reaction to nitrofurantoin ("Furadantin"). Med J Aust 1966; 2: 607-608

163. Satter E J. Furadantin anaphylaxis. J Urol 1966; 96: 86-87

164. Sollaccio P A, Ribaudo C A, Grace W J. Subacute pulmonary infiltration due to nitrofurantoin. Ann Intern Med 1966; 65: 1284-1286

165. Walton C H A. Asthma associated with the use of nitrofurantoin. Can Med Assoc J 1966; 94: 40-41

166. Bayer W L, Dawson R B, Jr, Kotin E. Allergic tracheobronchitis due to nitrofurantoin sensitivity. Report of a case. Dis Chest 1965; 48: 429-430

167. Conklin J D, Paul H E, Paul M F. The transport of nitrofurantoin through the lung. Life Sci 1965; 4: 1487-1492

168. Murray M J, Kronenberg R. Pulmonary reactions simulating cardiac pulmonary edema caused by nitrofurantoin. N Engl J Med 1965; 273: 1185-1187

169. Rasmussen J. Furadantinallergi. Et tilfaelde med pulmonale symptomer. Ugeskr Laeg 1964; 126: 167-168

170. Robinson B. Pleuropulmonary reaction to nitrofurantoin. JAMA 1964; 189: 239-240

171. Khorsandian R, Bremer E M, Nodine J H. Anaphylactic reaction caused by treatment with nitrofurantoin. JAMA 1963; 184: 500-502

172. Muir D C F, Stanton J A. Allergic pulmonary infiltration due to nitrofurantoin. Br Med J 1963; i: 1072

173. Israel H L, Diamond P. Recurrent pulmonary infiltration and pleural effusion due to nitrofurantoin sensitivity. N Engl J Med 1962; 266: 1024-1026

174. Lübbers P. Allergische Reaktion gegen Furadantin. Dtsch Med Wchschr 1962; 87: 2009-2211

175. Rebhun J. Sensitivity to furadantin. U S Armed Forces Med J 1956; 7: 1196-1200