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Antidepressants

3

See under specific drugs

Last update : 16/08/2012

I.b Pneumonitis (ILD)

1

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

2

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

1

II.a Pulmonary edema, noncardiogenic (NCPE)

2

II.b ARDS - Acute lung injury

2

V.b Eosinophilic pleural effusion

1

V.f Pneumothorax

1

VI.a Pulmonary embolism - Venous thrombosis/thromboembolism

1

VI.b Pulmonary arterial hypertension

2

VI.y Pulmonary hypertension of the newborn (Persistent PHT)

2

IX.e Disordered breathing pattern - Cheynes-Stokes respiration

1

XII.d Myocarditis (can be fulminant)

2

Diagnosing DIRD

1

Drug and radiation history

2

Drug singularity - Correct identification of the drug

3

Consistent timing of exposure v. onset of symptoms

4

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

5

Careful exlusion of another cause

6

Remission of symptoms with removal of drug

7

Recurrence with rechallenge (rarely advisable)

8

Causality assessment

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