Pneumotox » Pattern » X.i - The immune reconstitution syndrome (IRCS)

X.i

May manifest with pulmonary infiltrates, respiratory distress, ARDS (PMID 19254644), lymphadenopathy and/or pleural effusion

Last update : 01/01/1970

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I.c I.e X.a X.i

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I.a I.m II.b VII.a X.a X.i X.k XI.d XV.c

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Diagnosing DIRD

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Drug and radiation history

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Drug singularity - Correct identification of the drug

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Consistent timing of exposure v. onset of symptoms

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Clinical, imaging, BAL, pathological pattern consistent with the specific drug

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Careful exlusion of another cause

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Remission of symptoms with removal of drug

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Recurrence with rechallenge (rarely advisable)

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Causality assessment