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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Docetaxel

3

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

1
Last update : 18/08/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Paclitaxel
5

Publications

Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer.
The New England journal of medicine 2015 Jul 09;373;123-35 2015 Jul 09

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