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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Fluids, i.v.

3

II.h Overload pulmonary edema (including posttransfusional (TACO))

3
Last update : 29/11/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Malfunctioning Pediatric infusion set leading to accidental fluid overload and pulmonary edema.
Journal of anaesthesiology, clinical pharmacology 2014 Oct;30;579-81 2014 Oct
Cardiopulmonary effects of volume expansion in man: radiographic manifestations.
AJR. American journal of roentgenology 1985 Feb;144;289-93 1985 Feb

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