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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Iodine, radioactive (131I)

2

I.v Abnormal lung function/pulmonary physiology (PFTs) without necessarily imaging or clinical evidence

1
Last update : 01/05/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Radiation therapy, infusional (injected 131I or 90Y radioactivity)
2
Radiopharmaceuticals
2

Publications

Changes in the pulmonary function test after radioactive iodine treatment in patients with pulmonary metastases of differentiated thyroid cancer.
PloS one 2015;10;e0125114 2015

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