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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Vedolizumab

2

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

1
Last update : 22/04/2019
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Vedolizumab-associated diffuse interstitial lung disease in patients with ulcerative colitis: A case report.
World journal of clinical cases 2022 Feb 16;10;1716-1722 2022 Feb 16
Vedolizumab-Associated Acute Respiratory Distress Syndrome.
American journal of therapeutics 2018;25;e592-e593 2018

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