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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Daratumumab

2

XVII.a Respiratory tract infection incl. pneumonia

2
Last update : 06/10/2016
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Brief report: Clinical experiences after emergency use of daratumumab monotherapy for relapsed or refractory multiple myeloma in real practice.
Japanese journal of clinical oncology 2019 Jan 01;49;92-95 2019 Jan 01
Daratumumab, Lenalidomide, and Dexamethasone for Multiple Myeloma.
The New England journal of medicine 2016 Oct 06;375;1319-1331 2016 Oct 06

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