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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Perfluorocarbon (for liquid ventilation)

1

XVI.s Imaging: An area or areas of involvement with high attenuation numbers or metallic density

1
Last update : 11/03/2018
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

'Pseudo-calcifications': detection of perfluorocarbon residue on a computed tomography scan 15 years after liquid ventilation therapy at 3 months of age.
BMJ case reports 2018 Mar 05;2018; 2018 Mar 05

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