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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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nab-paclitaxel

2

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

1
Last update : 03/01/2019
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Clinical Characteristics and Risk Factors of Lung Injury Induced by Nab-Paclitaxel.
Drug design, development and therapy 2022;16;759-767 2022
Complete remission and fatal interstitial pneumonitis related to nab-paclitaxel in refractory small cell lung cancer: A case report and review of the literature.
Thoracic cancer 2012 Feb;3;84-87 2012 Feb

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