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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Infliximab

5

X.d Lupus - Lupus syndrome (see also Vd)

3
Last update : 23/02/2020
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Biosimilars
1
Infliximab biosimilar
1
TNF-alpha antagonists / inhibitors
5

Publications

Anti-tumour necrosis factor-α-induced lupus in a patient receiving infliximab for sarcoidosis.
Respirology case reports 2022 Aug;10;e01006 2022 Aug
Infliximab-Induced Lupus: A Case Report.
GE Portuguese journal of gastroenterology 2017 Mar;24;84-88 2017 Mar
Drug-specific risk and characteristics of lupus and vasculitis-like events in patients with rheumatoid arthritis treated with TNFi: results from BSRBR-RA.
RMD open 2017;3;e000314 2017
Recurrent drug-induced ANCA vasculitis in a patient with Crohn's colitis treated with infliximab: a potential contraindication to immunosuppressive therapy.
The American surgeon 2012 Dec;78;1406-8 2012 Dec
Safety of infliximab in Crohn's disease: a large single-center experience.
Inflammatory bowel diseases 2010 Dec;16;2109-16 2010 Dec
Arterial thrombosis with anti-phospholipid antibodies induced by infliximab.
European journal of dermatology : EJD 2007;17;546-7 2007
Assessment of antibodies to double-stranded DNA induced in rheumatoid arthritis patients following treatment with infliximab, a monoclonal antibody to tumor necrosis factor alpha: findings in open-label and randomized placebo-controlled trials.
Arthritis and rheumatism 2000 Nov;43;2383-90 2000 Nov

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