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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Infliximab

5

XVII.y Cryptococcus pulmonary and/or systemic infection

1
Last update : 15/01/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Biosimilars
1
Infliximab biosimilar
1
TNF-alpha antagonists / inhibitors
5

Publications

Symptomless Pulmonary Cryptococcosis in a Psoriatic Arthritis Patient during Infliximab Therapy.
Annals of dermatology 2016 Apr;28;269-70 2016 Apr
Possible pulmonary cryptococcosis in a patient with Crohn's disease during anti-tumor necrosis factor-alpha treatment: a case report and literature review.
Japanese journal of infectious diseases 2012;65;461-4 2012
Asymptomatic pulmonary cryptococcosis in a patient with Crohn's disease on infliximab: case report.
Inflammatory bowel diseases 2011 Jul;17;1637-8 2011 Jul

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