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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Interleukin 2 (IL2)

3

V.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

2
Last update : 14/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

[Radiologic characteristics of the thorax during therapy with interleukin-2].
La Radiologia medica 1992 Oct;84;368-71 1992 Oct
Chest roentgenographic abnormalities in IL-2 recipients. Incidence and correlation with clinical parameters.
Chest 1992 Mar;101;746-52 1992 Mar
Pathogenesis of pulmonary edema during interleukin-2 therapy: correlation of chest radiographic and clinical findings in 54 patients.
AJR. American journal of roentgenology 1991 Feb;156;281-5 1991 Feb
Cardiorespiratory effects of immunotherapy with interleukin-2.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989 Jan;7;7-20 1989 Jan

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