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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Levodopa (l-DOPA)

1

IX.b Respiratory dyskinesia

1
Last update : 24/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Unilateral GPi-DBS as a treatment for levodopa-induced respiratory dyskinesia in Parkinson disease.
The neurologist 2011 Sep;17;282-5 2011 Sep
Respiratory dyskinesia. An underrecognized phenomenon.
Chest 1994 Jun;105;1826-32 1994 Jun
Respiratory dysfunction due to L-dopa therapy for parkinsonism: diagnosis using serial pulmonary function tests and respiratory inductive plethysmography.
The American journal of medicine 1990 Jul;89;109-14 1990 Jul

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