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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Lidocaine (lignocaine, xylocaine)

3

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

2
Last update : 15/04/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anesthetic agents (local, topical)
3
Xylocaine
3

Publications

Bronchospasm and anaphylactic shock following lidocaine aerosol inhalation in a patient with butane inhalation lung injury.
Allergy, asthma & immunology research 2011 Oct;3;280-2 2011 Oct
Life-threatening anaphylactic reaction after the administration of airway topical lidocaine.
Pediatric pulmonology 2011 May;46;505-8 2011 May
[Anaphylaxis caused by lidocaine].
Annales francaises d'anesthesie et de reanimation 1989;8;127-9 1989

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