The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
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Lidocaine (lignocaine, xylocaine)
Severe, catastrophic asthma attack (can be fatal)
Last update :
Drug and radiation history
Drug singularity - Correct identification of the drug
Consistent timing of exposure v. onset of symptoms
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
Careful exlusion of another cause
Remission of symptoms with removal of drug
Recurrence with rechallenge (rarely advisable)
More detailed checklist
See also under
Anesthetic agents (local, topical)
Bronchospasm and anaphylactic shock following lidocaine aerosol inhalation in a patient with butane inhalation lung injury.
Adrenaline through the endotracheal tube as an answer to severe bronchospasms caused by lidocaine.
Acute bronchospasm following administration of lidocaine.