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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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GLP-1 receptor antagonists (GLP-1RA)

2

XI.g Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)

2
Last update : 26/02/2026
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

The science of safety: adverse effects of GLP-1 receptor agonists as glucose-lowering and obesity medications.
The Journal of clinical investigation 2026 Feb 16;136; 2026 Feb 16
Semaglutide-Induced Silent Aspiration: An Unrecognised Cause of Organising Pneumonia.
Respirology case reports 2025 Jul;13;e70249 2025 Jul

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