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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Methysergide

2

V.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

1
Last update : 10/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Ergots, ergot alkaloids, ergolines
4

Publications

[Pleuro-pulmonary fibrosis caused by methysergide].
La Nouvelle presse medicale 1981 Jul 04;10;2440-1 1981 Jul 04
Pleural thickening caused by Sansert and Ergotrate in the treatment of migraine.
AJR. American journal of roentgenology 1980 Aug;135;375-7 1980 Aug
Pleural effusion and fibrosis secondary to Sansert administration.
The Annals of thoracic surgery 1973 Mar;15;295-8 1973 Mar
Pleural effusion and fibrosis during treatment with methysergide.
British medical journal 1970 Mar 07;1;605-6 1970 Mar 07

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