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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Nadolol

1

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 06/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Beta-blockers
5

Publications

Response to salbutamol in patients with mild asthma treated with nadolol.
The European respiratory journal 2010 Oct;36;963-5 2010 Oct
The safety and effects of the beta-blocker, nadolol, in mild asthma: an open-label pilot study.
Pulmonary pharmacology & therapeutics 2008;21;134-41 2008

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