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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Pergolide

3

V.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

1
Last update : 09/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Pergolide-induced lung disease in patients with Parkinson's disease.
Respiratory medicine 2002 Jul;96;548-50 2002 Jul
Pleuropulmonary disease due to pergolide use for restless legs syndrome.
Chest 2001 Jul;120;313-6 2001 Jul
Pergolide-induced dyspnea, bilateral pleural effusion and peripheral edema.
Respiration; international review of thoracic diseases 2000;67;580-2 2000

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