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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Practolol

3

V.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

1
Last update : 31/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
More detailed checklist
See also under
Beta-blockers
5

Publications

Pleural fibrosis after practolol therapy.
Thorax 1978 Dec;33;822-4 1978 Dec
[Bilateral pleural effusion after practolol (author's transl)].
Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis 1977 May 31;66;676-8 1977 May 31
Letter: Pleural effusions after practolol.
Lancet (London, England) 1976 Jan 10;1;89 1976 Jan 10
Untoward effects associated with practolol administration: oculomucocutaneous syndrome.
British medical journal 1975 Mar 15;1;595-8 1975 Mar 15
Letter: Pleural effusions after practolol.
Lancet (London, England) 1975 Dec 13;2;1202 1975 Dec 13

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