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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Vindesine

2

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 31/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

[Respiratory complications of the vinorelbine-mitomycin combination].
Revue des maladies respiratoires 1999 Feb;16;81-4 1999 Feb
Acute pulmonary toxicity associated with high-dose vinorelbine and mitomycin C.
Annals of oncology : official journal of the European Society for Medical Oncology 1996 Nov;7;973-5 1996 Nov
Syndrome of acute dyspnea related to combined mitomycin plus vinca alkaloid chemotherapy.
American journal of clinical oncology 1995 Jun;18;245-50 1995 Jun

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