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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Nimesulide

1

IV.c Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)

1
Last update : 20/01/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
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Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Nonsteroidal anti-inflammatory drugs (NSAIDs)
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Publications

Fatal bronchiolitis obliterans complicating Stevens-Johnson syndrome following treatment with nimesulide: a case report.
Annals of tropical paediatrics 2011;31;259-61 2011

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