Bleomycin-induced ARDS can be hyperacute and fatal in a few days. Although oxygen may potentiate bleomycin toxicity, exposure to oxygen later in life after temination of treatment may have no detrimental consequences (PMID 23045915).
Last update :02/12/2013
Drug and radiation history
Drug singularity - Correct identification of the drug
Consistent timing of exposure v. onset of symptoms
Clinical, imaging, BAL, pathological pattern consistent with the specific drug