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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Alemtuzumab

1

XVII.h Nontuberculous pulmonary mycobacterial infection/superinfection

1
Last update : 31/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Rapidly growing non-tuberculous mycobacterial infection in a renal transplant patient after alemtuzumab induction.
Transplant infectious disease : an official journal of the Transplantation Society 2014 Oct;16;847-52 2014 Oct
Mycobacterium avium complex infection after alemtuzumab therapy for chronic lymphocytic leukemia.
Pharmacotherapy 2008 Feb;28;281-4 2008 Feb
Tuberculosis due to Mycobacterium bovis after alemtuzumab administration.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003 Jul 15;37;e27-8 2003 Jul 15

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