The DLCO/KCO are impacted more often than volumes and flows. Changes concomitant with the administration of chemotherapy, and tend to resolve after completion of treatment. Residual defect may persist longterm
v2.2
The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
See also under