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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Paraquat

5

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

2
Last update : 13/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Glyphosate
2

Publications

Combined initial cyclophosphamide with repeated methylprednisolone pulse therapy for severe paraquat poisoning from dermal exposure.
Journal of toxicology. Clinical toxicology 2003;41;877-81 2003
Paraquat poisoning: findings on chest radiography and CT in 42 patients.
AJR. American journal of roentgenology 1991 Oct;157;697-701 1991 Oct

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