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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Radiation therapy (medium term & late effects)

5

XI.v Rib fracture

2
Last update : 09/02/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Radiation therapy (early effects)
5
Radiation therapy to the breast
4
Radiation therapy to the chest
5
Radiation therapy, infusional (injected 131I or 90Y radioactivity)
2
Radiation therapy, mantle-field-
5
Radiation therapy, stereotactic (SBRT)
5

Publications

Rib fracture after stereotactic radiotherapy for primary lung cancer: prevalence, degree of clinical symptoms, and risk factors.
BMC cancer 2013 Feb 07;13;68 2013 Feb 07
Radiation-induced rib fractures after hypofractionated stereotactic body radiation therapy of non-small cell lung cancer: a dose- and volume-response analysis.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009 Jun;91;360-8 2009 Jun

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