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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Radiation therapy to the chest

5

XIX.a BAL: An excess proportion of lymphocytes

2
Last update : 02/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Radiation therapy (early effects)
5
Radiation therapy (endobronchial brachytherapy)
2
Radiation therapy (medium term & late effects)
5
Radiation therapy to the breast
4
Radiation therapy, infusional (injected 131I or 90Y radioactivity)
2
Radiation therapy, mantle-field-
5
Radiation therapy, stereotactic (SBRT)
5
Radioactive seeds
2

Publications

Bronchoalveolar lavage in bronchiolitis obliterans organizing pneumonia primed by radiation therapy to the breast.
The Journal of allergy and clinical immunology 2000 Feb;105;239-44 2000 Feb
Radiation-induced pneumonitis in the "nonirradiated" lung.
Mayo Clinic proceedings 1999 Jan;74;27-36 1999 Jan
Chronic lymphocytic alveolitis with migrating pulmonary infiltrates after localized chest wall irradiation.
Acta clinica Belgica 1998 Feb;53;39-43 1998 Feb

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