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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Carbamazepine
3
I.c
Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
2
Last update :
20/01/2012
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anticonvulsants
Publications
Carbamazepine-induced interstitial pneumonitis in a lung transplant patient.
[Acute eosinophilic pneumonia due to hypersensitivity to carbamazepine].
Carbamazepine and the lung.
[Immuno-allergic side effects induced by the administration of carbamazepine. Case contribution].
Pulmonary eosinophilia associated with carbamazepine.
Pulmonary eosinophilia and asthma associated with carbamazepine.
Acute hypersensitivity pneumonitis associated with carbamazepine therapy.
Acute pulmonary hypersensitivity to carbamazepine.
