Pneumotox » Drug » Tofacitinib » I.b

Tofacitinib

ILD incidence in RA patients similar in tofacitinib- and placebo-exposed patients (PMID 32826657)

Last update : 18/08/2023

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment