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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Corticosteroids, inhaled (ICS)

5

VIII.j Laryngeal disorder-Laryngeal nerve palsy (dysphonia, hoarseness)

5
Last update : 11/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Beclomethasone
2
Budesonide (inhaled)
3
Corticosteroids, systemic (oral, parenteral)
5
Fluticasone (inhaled - ICS)
4

Publications

Tracheobronchopathy From Inhaled Corticosteroids.
Chest 2017 Dec;152;1296-1305 2017 Dec
Voice evaluation in asthma patients using inhaled corticosteroids.
Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat 2016;26;101-8 2016
Dysphonia associated with the use of inhaled corticosteroids.
Current opinion in otolaryngology & head and neck surgery 2015 Jun;23;255-9 2015 Jun
Practical considerations for dysphonia caused by inhaled corticosteroids.
Mayo Clinic proceedings 2012 Sep;87;901-4 2012 Sep
Local oropharyngeal side effects of inhaled corticosteroids in patients with asthma.
Allergy 2006 May;61;518-26 2006 May
Corticosteroid-induced laryngeal disorders in asthma.
Medical science monitor : international medical journal of experimental and clinical research 2006 Aug;12;CR351-4 2006 Aug
Dysphonia caused by inhaled steroids: recognition of a characteristic laryngeal abnormality.
Thorax 1983 Nov;38;813-21 1983 Nov
Administration of cortisone by the aerosol method in the treatment of bronchial asthma.
The New England journal of medicine 1951 Aug 23;245;293-4 1951 Aug 23

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