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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
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Chloroquine
3
XII.m
Cardiac- cardiorespiratory/pulmonary arrest
1
Last update :
26/03/2015
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Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Hydroxychloroquine
Malaria prophylaxis
Mefloquine
Publications
[Acute chloroquine intoxication--rare, but always serious: case reports and literature review].
Suicidal chloroquine poisoning: clinical course, autopsy findings, and chemical analysis.
Intensive therapy for chloroquine poisoning. A review of 29 cases.
CHLOROQUINE POISONING IN A CHILD.