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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Eptifibatide

2

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

2
Last update : 05/10/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Diffuse alveolar hemorrhage; An under-diagnosed and rare complication of glycoprotein IIb/IIIa inhibitors.
Journal of cardiovascular and thoracic research 2022;14;201-204 2022
A retrospective analysis and case series of glycoprotein IIb/IIIa inhibitor associated diffuse alveolar hemorrhage: two case reports.
Cases journal 2009 Jul 30;2;8553 2009 Jul 30
Eptifibatide overdose.
International journal of cardiology 2009 Jan 24;131;430-2 2009 Jan 24
Alveolar hemorrhage: an underdiagnosed complication of treatment with glycoprotein IIb/IIIa inhibitors.
Journal of interventional cardiology 2006 Aug;19;356-63 2006 Aug
Alveolar hemorrhage associated with periprocedural eptifibatide administration.
The Journal of invasive cardiology 2004 Jun;16;341-2 2004 Jun

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