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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Ticagrelor

5

IX.e Disordered breathing pattern - Cheynes-Stokes respiration

1
Last update : 27/09/2017
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Dyspnea or Cheyne-Stokes respiration associated with Ticagrelor?
Sleep medicine 2018 Mar;43;4-6 2018 Mar
Reversal of Ticagrelor-Induced Arrhythmias and Cheyne-Stokes Respiration With Aminophylline Infusion.
Journal of cardiovascular pharmacology 2017 Nov;70;290-292 2017 Nov

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