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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Antituberculous chemotherapy

2

X.a DRES syndrome - DRESS-like reaction

1
Last update : 07/01/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Ethambutol
1
Isoniazid - INH
2
Para-aminosalicylic acid (PAS)
1
Rifampicin
1

Publications

Prevalence and Clinical Features of Drug Reactions With Eosinophilia and Systemic Symptoms Syndrome Caused by Antituberculosis Drugs: A Retrospective Cohort Study.
Allergy, asthma & immunology research 2019 Jan;11;90-103 2019 Jan
Drug reaction with eosinophilia and systemic symptoms syndrome is not uncommon and shows better clinical outcome than generally recognised.
Allergologia et immunopathologia 2015;43;19-24 2015
Drug Rash with Eosinophilia and Systemic Symptoms Syndrome Due to Anti-TB Medication.
Journal of family medicine and primary care 2013 Jan;2;83-5 2013 Jan

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