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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Status post-thoracic/cardiovascular surgery

4

V.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

3
Last update : 12/11/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Status post-coronary artery bypass graft (CABG)
3

Publications

Prevalence and clinical course of pleural effusions at 30 days after coronary artery and cardiac surgery.
American journal of respiratory and critical care medicine 2002 Dec 15;166;1567-71 2002 Dec 15
Symptomatic persistent post-coronary artery bypass graft pleural effusions requiring operative treatment : clinical and histologic features.
Chest 2001 Mar;119;795-800 2001 Mar

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