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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Methylene blue

1

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

1
Last update : 22/08/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Dyes
3

Publications

Anaphylactic-like reaction to methylene blue: case report and review of perioperative hypersensitivity reactions.
Plastic and reconstructive surgery 2012 Jul;130;98e-105e 2012 Jul
Anaphylaxis reaction of a breast cancer patient to methylene blue during breast surgery with sentinel node mapping.
Acta oncologica (Stockholm, Sweden) 2010 Aug;49;877-8 2010 Aug

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