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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Lipiodol - Iodinated/iodized oil (RCM)

2

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

1
Last update : 21/02/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Doxorubicin - Adriamycin
3
Lipids (parenteral)
3
Oil-/lipid-based formulations (parenteral)
3
Radiocontrast media (RCM)
5
Transhepatic arterial chemoembolization (TACE)
3

Publications

Intra-alveolar hemorrhage following bipedal lymphography.
Intensive care medicine 1996 Jun;22;614-5 1996 Jun
Intrapulmonary hemorrhage with anemia after lymphography.
The New England journal of medicine 1971 Dec 09;285;1364-5 1971 Dec 09

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