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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Hyaluronate - Hyaluronic acid

1

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

1
Last update : 23/05/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Hyaluronic acid (inhaled)
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Publications

Diffuse alveolar haemorrhage and myocardial infarction: life-threatening effects from self-injected hyaluronic acid dermal filler.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 2021 Jul 22;91; 2021 Jul 22
Hyaluronic acid-induced diffuse alveolar hemorrhage: unknown complication induced by a well-known injectable agent.
Annals of translational medicine 2019 Jan;7;13 2019 Jan
A case of diffuse alveolar hemorrhage associated with hyaluronic acid dermal fillers.
The American journal of case reports 2014;15;199-202 2014

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