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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Nivolumab

5

X.d Lupus - Lupus syndrome (see also Vd)

1
Last update : 12/05/2018
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Avelumab
1
Durvalumab
3
Immune checkpoint inhibitors (ICI) - ICI combinatorial Rx
5
Lambrolizumab
4
PD-1/PD-L1-inhibitors or blocking agents/drugs
5
Pembrolizumab
5

Publications

Drug-induced systemic lupus erythematosus: should immune checkpoint inhibitors be added to the evolving list?
Annals of the rheumatic diseases 2021 Jul;80;e120 2021 Jul
[Unexpected adverse events of immunotherapies in non-small cell lung cancer: About 2 cases].
Revue de pneumologie clinique 2017 Dec;73;326-330 2017 Dec

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