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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cyproterone

1

VI.a Pulmonary embolism - Venous thrombosis/thromboembolism

2
Last update : 21/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Androgen deprivation therapy (Antiandrogens)
2
Contraceptive drugs or pills (oral)
3

Publications

Chronic thromboembolic pulmonary hypertension complicating long-term cyproterone acetate therapy.
European respiratory review : an official journal of the European Respiratory Society 2014 Jun;23;260-3 2014 Jun
Thromboembolic events in women exposed to hormonal contraception or cyproterone acetate in 2012: a cross-sectional observational study in 30 French public hospitals.
Drug safety 2014 Apr;37;269-82 2014 Apr
Risk of venous thromboembolism with cyproterone or levonorgestrel contraceptives.
Lancet (London, England) 2001 Oct 27;358;1427-9 2001 Oct 27

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