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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cytosine arabinoside - Aracytine - Cytarabine - Ara-C

3

XII.c Pericardial effusion (w/wo tamponade)

1
Last update : 26/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Cytarabine-induced pericarditis: a case report and review of the literature of the cardio-pulmonary complications of cytarabine therapy.
Leukemia research 1995 Feb;19;141-4 1995 Feb

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