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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Pacemaker leads - Implantable cardiac devices

4

V.n Hemopericardium - Bloody pericardial effusion

1
Last update : 05/01/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Pacemaker lead related myocardial perforation.
The American journal of emergency medicine 2022 Mar;53;281.e1-281.e3 2022 Mar
Case Records of the Massachusetts General Hospital. Case 19-2015. A 71-Year-Old Man with Chest Pain and Shortness of Breath.
The New England journal of medicine 2015 Jun 18;372;2438-46 2015 Jun 18
Incidence and predictors of pericardial effusion after permanent heart rhythm device implantation: prospective evaluation of 968 consecutive patients.
Circulation journal : official journal of the Japanese Circulation Society 2013;77;975-81 2013
Pacemaker lead perforation causing hemopericardium eight years after implantation.
Indian heart journal 2013;65;331-3 2013

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