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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Breast implants - Augmentation mammaplasty (w/wo evidence for leakage/rupture)

4

V.w Silicone pleural nodules - Pleural siliconomas

1
Last update : 05/05/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Silicone, fluid
5

Publications

Disseminated Pleural Siliconoma Mimicking Malignant Pleural Mesothelioma.
The Annals of thoracic surgery 2015 Dec;100;2339-40 2015 Dec
Silicone thorax due to a ruptured breast implant.
Chest 2005 May;127;1854-7 2005 May

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