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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Rocuronium

1

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

1
Last update : 17/02/2014
 
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Diagnosing DIRD
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Drug and radiation history
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Drug singularity - Correct identification of the drug
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Consistent timing of exposure v. onset of symptoms
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Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Curares
5
Neuromuscular blocking agents (NMBA-NMBD)
5
Sugammadex
1

Publications

Rocuronium-induced anaphylaxis: a case report.
JA clinical reports 2019 Dec 06;5;81 2019 Dec 06
A Case of Rocuronium-Induced Anaphylactic Shock in an Asthmatic Child.
Anesthesia progress 2018;65;58-59 2018
[A Case of Rocuronium-induced Anaphylaxis in a Man with Kounis Syndrome in which Basophil Activation Test was Valuable in Determining the Causative Agent].
Masui. The Japanese journal of anesthesiology 2017 Apr;66;424-430 2017 Apr
Multiple cross-reactivity to several types of neuromuscular blocking agents in a patient with rocuronium anaphylaxis.
Korean journal of anesthesiology 2013 Nov;65;473-4 2013 Nov
Case of anaphylaxis induced by rocuronium treated with sugammadex.
Brazilian journal of anesthesiology (Elsevier) 2013;63;511 2013
Histaminoid reactions associated with rocuronium.
British journal of anaesthesia 2000 Jan;84;108-11 2000 Jan
Anaphylactic reaction to rocuronium bromide.
Anaesthesia and intensive care 1996 Oct;24;601-4 1996 Oct

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