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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Dextran

2

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

1
Last update : 30/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Hyskon induced pulmonary hemorrhage.
Journal of clinical anesthesia 1995 Jun;7;323-5 1995 Jun
Dextran 70 embolization. Another cause of pulmonary hemorrhage, coagulopathy, and rhabdomyolysis.
Chest 1993 Aug;104;631-3 1993 Aug

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