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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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X.ai

The Ovarian Hyperstimulation Syndrome (OHS)

Last update : 01/01/1970
 

Causative drugs

1

Ovarian stimulation

II.a II - Pulmonary edema - Acute lung injury - ARDS
II.a - Pulmonary edema, noncardiogenic (NCPE)
V.a V - Pleural and/or pericardial involvement
V.a - Pleural effusion (uni- or bilateral) (can accompany DI-LDs)
V.e V - Pleural and/or pericardial involvement
V.e - Hemothorax - Serosanguineous pleural effusion
V.g V - Pleural and/or pericardial involvement
V.g - Effusions of the ovarian hyperstimulation syndrome (OHSS)
X.c X - Systemic/Distant conditions, syndromes and reactions
X.c - Capillary leak syndrome (CLS)
X.ai X - Systemic/Distant conditions, syndromes and reactions
X.ai - The Ovarian Hyperstimulation Syndrome (OHS)
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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