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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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IV.ai

Bronchiolitis obliterans, post-Stevens-Johnson

Last update : 01/01/1970
 

Causative drugs

1

Cefuroxime

IV.c IV - Airway involvement
IV.c - Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)
IV.ai IV - Airway involvement
IV.ai - Bronchiolitis obliterans, post-Stevens-Johnson
1
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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