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Radiation therapy (medium term & late effects)

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

Although apparently effective, corticosteroid therapy is not indicated in every patient and may promote relapse or relapses upon tapering (PMID 30705815)

Last update : 29/03/2019

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

More detailed checklist

The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

Radiation therapy (medium term & late effects)

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

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